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McBride-Gagyi, Sara

Biography

Sara McBride-Gagyi is originally from South Carolina. She completed a B.S. in Mechanical Engineering from Clemson University (2004),  MS and PhD degrees in Biomedical Engineering from Case Western Reserve University (2008 & 2011), and post-doctoral training at Washington University in St. Louis in the Department of Orthopedics (2014). As an undergraduate, Dr. McBride-Gagyi co-oped at General Electric and Rockwell Automation. Prior to joining OSU in 2022, Dr. McBride-Gagyi was an Assistant Professor in Orthopedic Surgery at Saint Louis University. Dr. McBride-Gagyi is especially passionate about increasing diversity in all STEMM fields and supporting the development of the next generation of biomedical engineers.  

Expertise

Dr. McBride-Gagyi's research focuses on bone development and repair. Her lab routinely uses rodent genetic and surgical models in conjunction with biological, mechanical, and imaging-based experimental techniques to assess bone form and function. She also collaborates with engineers and chemists to develop new tools for use with microCT. Currently, her main research focus is elucidating the biological mechanisms that support massive graft survival and bone reconstruction using Masquelet's Induced Membrane Technique for segmental bone defect repair. Studying this procedure will not only allow for technique optimization and the development of better diagnostics and therapeutics but also likely reveal novel bone biology that could be applied to other anabolic bone scenarios