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Derek Hansford

  • Associate Professor, Materials Science Engineering
  • Associate Professor, Biomedical Engineering
  • 293 Bevis Hall
    1080 Carmack Road
    Columbus, OH 43210
  • 614-688-3449

About

Education

  • B.S., Case Western Reserve University, 1994
  • Ph.D., University of California at Berkeley, 1999

 

Key Honors and Distinctions

  • Herman R. Weed Excellence in Teaching Award, Department of Biomedical Engineering, OSU (2016)
  • Lumley Research Award, College of Engineering, OSU (2013)

 

RESEARCH AREAS – Hansford Lab

  • Micro/Nanotechnology devices and fabrication; Biomaterials

 

  • PUBLICATIONS 

https://scholar.google.com/citations?user=G432w_MAAAAJ&hl=en

 

  • PATENTS
    • Essenpreis, Matthias; Desai, Tejal A; Ferrari, Mauro; Hansford, Derek J. "Implantable Analyte Sensor." Patent #6405066
    • Guan, Jingjiao; Hansford, Derek J; Lee, L James. "Self-folding polymer microparticles." Patent #7364675
    • Hansford, Derek J; Walczak, Robbie J; Boiarski, Anthony, A; Albert Terrence Conlisk. "Nanopump devices and methods." Patent #7799197
    • Epstein, Arthur J; Feinberg, Steven E; Hansford, Derek J; Yang, Yanyin. “Electrical stimulation of cell and tissue growth with two- and three-dimensionally patterned electrodes.” Patent #8478422.

Professor Hansford’s research investigates the bio-material interface through the use of advanced micro/nanofabrication techniques. Our fabrication techniques have been demonstrated on a wide variety of biomaterials and advanced functional materials, and can be used for planar, curved, and multi-level microstructures for enhancing and controlling the attachment of cells and tissues. We use these engineered biomaterial surfaces to study cellular behaviors from cancer cell migration behaviors through enhanced implant-tissue attachment. We also develop advanced microdevices for studying cells and manipulating bio-fluids at the micro/nanoscale for cell and biomolecular manipulation as well as modulation of the cellular microenvironment.

Involves the development of generalized microfabrication protocols for polymers as well as advanced applications of polymer, glass, and silicon microdevices for biomedical applications.  The Hansford lab has expertise in microfabrication of a wide array of biomaterials (especially functional polymers), modification of materials surfaces for enhanced biocompatibility, and design of bioMEMS devices for cellular interactions.

 

Chapters

2012

  • 2012. "Micropatterned coatings for guided tissue regeneration in dental implantology." In Cell Interaction, edited by S Gowder,
  • 2012. "Propagation of human bone marrow stem cells for craniofacial applications." In Stem cells and cancer stem cells (Vol. 7): Therapeutic applications in disease and injury, edited by MA Hayat,

2003

  • 2003. "Medical therapy: The next frontier of biochip and biomedical nanotechnology." In Biochips: Technology and Applications, edited by W-L Xing, J Cheng,

2001

  • 2001. ""Nano-scale size-based biomolecular separation technology"." In Biochip Technologies, edited by L. Kricka and J. Cheng,

Journal Articles

2019

  • Dorayappan, K.D.P.; Gardner, M.L.; Hisey, C.L.; Zingarelli, R.A. et al., 2019, "A Microfluidic Chip Enables Isolation of Exosomes and Establishment of Their Protein Profiles and Associated Signaling Pathways in Ovarian Cancer.." Cancer Res 79, no. 13, 3503-3513 - 3503-3513.

2018

  • Tao, K.; Fan, Z.; Sun, L.; Makam, P. et al., 2018, "Quantum confined peptide assemblies with tunable visible to near-infrared spectral range.." Nat Commun 9, no. 1, 3217 - 3217.
  • Alvarez-Escobar, M.; Freitas, S.C.; Hansford, D.; Monteiro, F.J. et al., 2018, "Soft Lithography and Minimally Human Invasive Technique for Rapid Screening of Oral Biofilm Formation on New Microfabricated Dental Material Surfaces.." Int J Dent 2018, 4219625 - 4219625.
  • Hisey, C.L.; Dorayappan, K.D.P.; Cohn, D.E.; Selvendiran, K. et al., 2018, "Microfluidic affinity separation chip for selective capture and release of label-free ovarian cancer exosomes.." Lab Chip 18, no. 20, 3144-3153 - 3144-3153.

2017

  • Higuita-Castro, N.; Nelson, M.T.; Shukla, V.; Agudelo-Garcia, P.A. et al., 2017, "Using a Novel Microfabricated Model of the Alveolar-Capillary Barrier to Investigate the Effect of Matrix Structure on Atelectrauma.." Sci Rep 7, no. 1, 11623 - 11623.

2016

  • Carvalho, A.; Pelaez-Vargas, A.; Hansford, D.J.; Fernandes, M.H. et al., 2016, "Effects of Line and Pillar Array Microengineered SiO2 Thin Films on the Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells.." Langmuir 32, no. 4, 1091-1100 - 1091-1100.
  • Gallego-Perez, D.; Chang, L.; Shi, J.; Ma, J. et al., 2016, "On-Chip Clonal Analysis of Glioma-Stem-Cell Motility and Therapy Resistance.." Nano Lett 16, no. 9, 5326-5332 - 5326-5332.

2015

  • Malkoc, V.; Gallego-Perez, D.; Nelson, T.; Lannutti, J.J. et al., 2015, "Controlled neuronal cell patterning and guided neurite growth on micropatterned nanofiber platforms." Journal of Micromechanics and Microengineering 25, no. 12,

2014

  • Laranjeira, M.S.; Carvalho, Â.; Pelaez-Vargas, A.; Hansford, D. et al., 2014, "Modulation of human dermal microvascular endothelial cell and human gingival fibroblast behavior by micropatterned silica coating surfaces for zirconia dental implant applications.." Sci Technol Adv Mater 15, no. 2, 025001 - 025001.
  • Benavente-Babace, A.; Gallego-Pérez, D.; Hansford, D.J.; Arana, S. et al., 2014, "A Versatile Microfabricated Platform for Single-Cell Studies." IFMBE Proceedings 41, 864-867 - 864-867.
  • Benavente-Babace, A.; Gallego-Pérez, D.; Hansford, D.J.; Arana, S. et al., 2014, "Single-cell trapping and selective treatment via co-flow within a microfluidic platform.." Biosens Bioelectron 61, 298-305 - 298-305.

2013

  • Pelaez-Vargas,Alejandro; Gallego-Perez,Daniel; Carvalho,Angela; Fernandes,Maria,H; Hansford,Derek,J; Monteiro,Fernando,J, 2013, "Effects of density of anisotropic microstamped silica thin films on guided bone tissue regenerationIn vitro study." JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS 101B, no. 5, 762-769 - 762-769.
  • Dinan, B.; Gallego-Perez, D.; Lee, H.; Hansford, D. et al., 2013, "Thermally grown TiO2 nanowires to improve cell growth and proliferation on titanium based materials." Ceramics International 39, no. 5, 5949-5954 - 5949-5954.
  • Min, Y.; Yang, Y.; Poojari, Y.; Liu, Y. et al., 2013, "Sulfonated polyaniline-based organic electrodes for controlled electrical stimulation of human osteosarcoma cells.." Biomacromolecules 14, no. 6, 1727-1731 - 1727-1731.
  • DINAN,B; Gallego-Perez,D; LEE,H; Hansford,D; Akbar,S,A, 2013, "Thermally grown TiO2 nanowires to improve cell growth and proliferation on titanium based materials." CERAMICS INTERNATIONAL 39, no. 5, 5949-5954 - 5949-5954.
  • Pelaez-Vargas, A.; Gallego-Perez, D.; Carvalho, A.; Fernandes, M.H. et al., 2013, "Effects of density of anisotropic microstamped silica thin films on guided bone tissue regeneration--in vitro study.." J Biomed Mater Res B Appl Biomater 101, no. 5, 762-769 - 762-769.
  • Fei, Z.; Wu, Y.; Sharma, S.; Gallego-Perez, D. et al., 2013, "Gene delivery to cultured embryonic stem cells using nanofiber-based sandwich electroporation.." Anal Chem 85, no. 3, 1401-1407 - 1401-1407.

2012

  • Carvalho, A.; Pelaez-Vargas, A.; Gallego-Perez, D.; Grenho, L. et al., 2012, "Micropatterned silica thin films with nanohydroxyapatite micro-aggregates for guided tissue regeneration.." Dent Mater 28, no. 12, 1250-1260 - 1250-1260.
  • Higuita-Castro, N.; Gallego-Perez, D.; Pelaez-Vargas, A.; García Quiroz, F. et al., 2012, "Reinforced Portland cement porous scaffolds for load-bearing bone tissue engineering applications.." J Biomed Mater Res B Appl Biomater 100, no. 2, 501-507 - 501-507.
  • Gallego-Perez, D.; Higuita-Castro, N.; Denning, L.; DeJesus, J. et al., 2012, "Microfabricated mimics of in vivo structural cues for the study of guided tumor cell migration.." Lab Chip 12, no. 21, 4424-4432 - 4424-4432.
  • Higuita-Castro,Natalia; Gallego-Perez,Daniel; Pelaez-Vargas,Alejandro; Garcia Quiroz,Felipe; Posada,Olga,M; Lopez,Luis,E; Sarassa,Carlos,A; Agudelo-Florez,Piedad; Monteiro,Fernando,J; Litsky,Alan,S; Hansford,Derek,J, 2012, "Reinforced Portland cement porous scaffolds for load-bearing bone tissue engineering applications." JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS 100B, no. 2, 501-507 - 501-507.
  • Gallego-Perez, D.; Higuita-Castro, N.; Reen, R.K.; Palacio-Ochoa, M. et al., 2012, "Micro/nanoscale technologies for the development of hormone-expressing islet-like cell clusters.." Biomed Microdevices 14, no. 4, 779-789 - 779-789.

2011

  • Pelaez-Vargas, A.; Gallego-Perez, D.; Magallanes-Perdomo, M.; Fernandes, M.H. et al., 2011, "Isotropic micropatterned silica coatings on zirconia induce guided cell growth for dental implants.." Dent Mater 27, no. 6, 581-589 - 581-589.
  • Gallego-Perez, D.; Higuita-Castro, N.; Quiroz, F.G.; Posada, O.M. et al., 2011, "Portland cement for bone tissue engineering: Effects of processing and metakaolin blends.." J Biomed Mater Res B Appl Biomater 98, no. 2, 308-315 - 308-315.
  • Yang, Y.; Min, Y.; Wu, J-C.; Hansford, D.J. et al., 2011, "Synthesis and characterization of cytocompatible sulfonated polyanilines.." Macromol Rapid Commun 32, no. 12, 887-892 - 887-892.
  • Gallego-Perez,Daniel; Higuita-Castro,Natalia; Quiroz,Felipe,García; Posada,Olga,M; López,Luis,E; Litsky,Alan,S; Hansford,Derek,J, 2011, "Portland cement for bone tissue engineering: Effects of processing and metakaolin blends.." Journal of biomedical materials research. Part B, Applied biomaterials 98, no. 2, 308-315 - 308-315.
  • Higuita-Castro, N.; Mihai, C.; Hansford, D.J.; Ghadiali, S.N., 2011, "Influence of Airway Wall Compliance on Epithelial Cell Injury during Cyclic Airway Reopening." FASEB JOURNAL 25,
  • Borteh, H.M.; Ferrell, N.J.; Butler, R.T.; Olesik, S.V. et al., 2011, "Peptide-induced patterning of gold nanoparticle thin films." Applied Surface Science 258, no. 1, 230-235 - 230-235.
  • Gallego-Perez, D.; Higuita-Castro, N.; Quiroz, F.G.; Posada, O.M. et al., 2011, "Portland cement for bone tissue engineering: Effects of processing and metakaolin blends." Journal of Biomedical Materials Research - Part B Applied Biomaterials 98 B, no. 2, 308-315 - 308-315.
  • Ferrell, N.; Woodard, J.; Hansford, D.J., 2011, "Measurement of cell forces using a microfabricated polymer cantilever sensor." Sensors and Actuators, A: Physical 170, no. 1-2, 84-89 - 84-89.
  • Gallego-Perez,Daniel; Higuita-Castro,Natalia; Garcia Quiroz,Felipe; Posada,Olga,M; Lopez,Luis,E; Litsky,Alan,S; Hansford,Derek,J, 2011, "Portland cement for bone tissue engineering: Effects of processing and metakaolin blends." JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS 98B, no. 2, 308-315 - 308-315.

2010

  • Sabbani, S.; Gallego-Perez, D.; Nagy, A.; James Waldman, W. et al., 2010, "Synthesis of silver-zeolite films on micropatterned porous alumina and its application as an antimicrobial substrate." Microporous and Mesoporous Materials 135, no. 1-3, 131-136 - 131-136.
  • Ferrell, N.; Yang, Y.; Hansford, D.J., 2010, "Micropatterning of sulfonated polyaniline using a soft lithography based lift-off process." Microsystem Technologies 16, no. 11, 1951-1956 - 1951-1956.
  • Gallego-Perez, D.; Higuita-Castro, N.; Sharma, S.; Reen, R.K. et al., 2010, "High throughput assembly of spatially controlled 3D cell clusters on a micro/nanoplatform.." Lab Chip 10, no. 6, 775-782 - 775-782.
  • Ferrell, N.; Gallego-Perez, D.; Higuita-Castro, N.; Butler, R.T. et al., 2010, "Vacuum-assisted cell seeding in a microwell cell culture system.." Anal Chem 82, no. 6, 2380-2386 - 2380-2386.
  • Gallego-Perez, D.; Ferrell, N.J.; Higuita-Castro, N.; Hansford, D.J., 2010, "Versatile methods for the fabrication of polyvinylidene fluoride microstructures.." Biomed Microdevices 12, no. 6, 1009-1017 - 1009-1017.
  • Quiroz, F.G.; Posada, O.M.; Gallego-Perez, D.; Higuita-Castro, N. et al., 2010, "Housekeeping gene stability influences the quantification of osteogenic markers during stem cell differentiation to the osteogenic lineage.." Cytotechnology 62, no. 2, 109-120 - 109-120.
  • Pelaez-Vargas, A.; Gallego-Perez, D.; Ferrell, N.; Fernandes, M.H. et al., 2010, "Early spreading and propagation of human bone marrow stem cells on isotropic and anisotropic topographies of silica thin films produced via microstamping.." Microsc Microanal 16, no. 6, 670-676 - 670-676.

2009

  • Schwan, S.; Ferrell, N.; Hansford, D.; Spohn, U. et al., 2009, "Measurement of mechanical forces generated by plant P-protein aggregates (forisomes).." Eur Biophys J 38, no. 4, 533-536 - 533-536.
  • Xu, J.; Dapino, M.J.; Gallego-Perez, D.; Hansford, D., 2009, "Microphone based on Polyvinylidene Fluoride (PVDF) micro-pillars and patterned electrodes." Sensors and Actuators, A: Physical 153, no. 1, 24-32 - 24-32.

2008

  • Xu, J.; Dapino, M.J.; Perez, D.G.; Hansford, D., 2008, "Acoustic sensor with PVDF micro-pillars and patterned electrodes." Proceedings of the ASME Conference on Smart Materials, Adaptive Structures and Intelligent Systems, SMASIS2008 1, 721-727 - 721-727.
  • Gallego, D.; Ferrell, N.; Sun, Y.; Hansford, D.J., 2008, "Multilayer micromolding of degradable polymer tissue engineering scaffolds." Materials Science and Engineering C 28, no. 3, 353-358 - 353-358.
  • Spiwak, A.J.B.; Horbal, A.; Leatherbury, R.; Hansford, D.J., 2008, "Extracorporeal tubing in the roller pump raceway: physical changes and particulate generation.." J Extra Corpor Technol 40, no. 3, 188-192 - 188-192.

2007

  • D Gallego, N Higuita, F Garcia, N Ferrell, and DJ Hansford, 2007, "Bioactive coatings on Portland cement substrates: Surface precipitation of Apatite-like crystals." Materials Science and Engineering C 28, 253-358 - 253-358.
  • M Palacio, B Bhushan, N Ferrell, and DJ Hansford, 2007, "Adhesion properties of polymer/silicon interfaces for biological micro/nanoelectromechanical systems applications." Jo Vac Sci Tech A 25, no. 4, 1275-1284 - 1275-1284.
  • Guan, J.; He, H.; Lee, L.J.; Hansford, D.J., 2007, "Fabrication of particulate reservoir-containing, capsulelike, and self-folding polymer microstructures for drug delivery.." Small 3, no. 3, 412-418 - 412-418.
  • Koulouridis,Stavros; Kiziltas,Gullu; Zhou,Yijun; Hansford,Derek,J; Volakis,John,L, 2007, "Polymer-ceramic composites for microwave applications: Fabrication and performance assessment." IEEE Trans. Microwave Theory and Techniques 12, no. 54, 4202-4208 - 4202-4208.
  • J Guan, LJ Lee, and DJ Hansford, 2007, "Fabrication of particulate-like polymer microstructures for drug delivery by soft lithography." Small 3, no. 3, 412-418 - 412-418.
  • N Ferrell and DJ Hansford, 2007, "Micro and nanoscale fabrication of polymer structures by soft lithography spin dewetting." Macromolecules Rapid Communications 28, 966-971 - 966-971.
  • Ferrell, N.; Woodard, J.; Hansford, D., 2007, "Fabrication of polymer microstructures for MEMS: sacrificial layer micromolding and patterned substrate micromolding.." Biomed Microdevices 9, no. 6, 815-821 - 815-821.
  • Ferrell, N.; Hansford, D., 2007, "Fabrication of micro- and nanoscale polymer structures by soft lithography and spin dewetting." Macromolecular Rapid Communications 28, no. 8, 966-971 - 966-971.
  • Kitzmiller, J.P.; Hansford, D.J.; Fortin, L.D.; Obrietan, K.H. et al., 2007, "Micro-field evoked potentials recorded from the porcine sub-dural cortical surface utilizing a microelectrode array.." J Neurosci Methods 162, no. 1-2, 155-161 - 155-161.
  • Palacio, M.; Bhushan, B.; Ferrell, N.; Hansford, D., 2007, "Nanomechanical characterization of polymer beam structures for BioMEMS applications." Sensors and Actuators, A: Physical 135, no. 2, 637-650 - 637-650.
  • Guan, J.; Ferrell, N.; Yu, B.; Hansford, D.J. et al., 2007, "Simultaneous fabrication of hybrid arrays of nanowires and micro/nanoparticles by dewetting on micropillars." Soft Matter 3, no. 11, 1369-1371 - 1369-1371.

2006

  • Guan, Jingjiao; Ferrell, Nicholas; James Lee, L; Hansford, Derek J, 2006, "Fabrication of polymeric microparticles for drug delivery by soft lithography.." Biomaterials 27, no. 21, 4034-4041 - 4034-4041.
  • Bhushan, B.; Hansford, D.; Lee, K.K., 2006, "Surface modification of silicon and polydimethylsiloxane surfaces with vapor-phase-deposited ultrathin fluorosilane films for biomedical nanodevices." Journal of Vacuum Science and Technology A: Vacuum, Surfaces and Films 24, no. 4, 1197-1202 - 1197-1202.
  • Butler, R.T.; Ferrell, N.J.; Hansford, D.J., 2006, "Spatial and geometrical control of silicification using a patterned poly-l-lysine template." Applied Surface Science 252, no. 20, 7337-7342 - 7337-7342.
  • B Bhushan, DJ Hansford, and KK Lee, 2006, "Surface modification of silicon and PDMS surfaces with vapor phase deposited ultrathin fluorosilane films for biomedical nanodevices." Journal of Vacuum Science and Technology A 4, no. 24, 1197-1202 - 1197-1202.
  • J Kitzmiller, DQ Beversdorf, and DJ Hansford, 2006, "Microfabrication of microelectrode arrays for neural column potentiometry." Biomedical Microdevices 8, 81-85 - 81-85.
  • Kitzmiller, J.; Beversdorf, D.; Hansford, D., 2006, "Fabrication and testing of microelectrodes for small-field cortical surface recordings.." Biomed Microdevices 8, no. 1, 81-85 - 81-85.
  • Guan, J.; Ferrell, N.; James Lee, L.; Hansford, D.J., 2006, "Fabrication of polymeric microparticles for drug delivery by soft lithography.." Biomaterials 27, no. 21, 4034-4041 - 4034-4041.
  • Koulouridis, S.; Kiziltas, G.; Zhou, Y.; Hansford, D.J. et al., 2006, "Polymer-ceramic composites for microwave applications: Fabrication and performance assessment." IEEE Transactions on Microwave Theory and Techniques 54, no. 12, 4202-4208 - 4202-4208.

2005

  • Lee, K.K.; Bhushan, B.; Hansford, D., 2005, "Nanotribological characterization of fluoropolymer thin films for biomedical micro/nanoelectromechanical system applications." Journal of Vacuum Science and Technology A: Vacuum, Surfaces and Films 23, no. 4, 804-810 - 804-810.
  • Guan, J.; He, H.; Hansford, D.J.; Lee, L.J., 2005, "Self-folding of three-dimensional hydrogel microstructures.." J Phys Chem B 109, no. 49, 23134-23137 - 23134-23137.
  • Guan, J.; Chakrapani, A.; Hansford, D.J., 2005, "Polymer microparticles fabricated by soft lithography." Chemistry of Materials 17, no. 25, 6227-6229 - 6227-6229.
  • G Wei, B Bhushan, N Ferrell, and DJ Hansford, 2005, "Nanomechanical characterization of materials for Polymer MEMS applications." Journal of Vacuum Science and Technology A 4, no. 23, 811-819 - 811-819.
  • Wei, G.; Bhushan, B.; Ferrell, N.; Hansford, D., 2005, "Microfabrication and nanomechanical characterization of polymer microelectromechanical system for biological applications." Journal of Vacuum Science and Technology A: Vacuum, Surfaces and Films 23, no. 4, 811-819 - 811-819.
  • KK Lee, B Bhushan, and DJ Hansford, 2005, "Vapor phase deposition of fluoropolymers and fluorosilanes for nanochannel applications." Journal of Vacuum Science and Technology A 4, no. 23, 804-810 - 804-810.
  • J Guan, H He, DJ Hansford, and LJ Lee, 2005, "Self-folding of three-dimensional hydrogel microstructures." Journal of Physical Chemistry B: Condensed Matter, Materials Surfaces, Interfaces, and Biophysics 49, no. 109, 23134-23137 - 23134-23137.
  • J Guan, A Chakrapani, and DJ Hansford, 2005, "Polymer microparticles fabricated by soft lithography." Chemistry of Materials 25, no. 17, 6627-6629 - 6627-6629.

2003

  • Zheng, Z.; Hansford, D.J.; Conlisk, A.T., 2003, "Effect of multivalent ions on electroosmotic flow in micro- and nanochannels.." Electrophoresis 24, no. 17, 3006-3017 - 3006-3017.
  • Zheng, Zhi; Hansford, Derek, J; Conlisk, Albert T, 2003, "Effect of multivalent ions on electroosmotic flow in micro- and nanochannels.." Electrophoresis 24, no. 17, 3006-17 - 3006-17.

2002

  • Conlisk, A.T.; McFerran, J.; Zheng, Z.; Hansford, D., 2002, "Mass transfer and flow in electrically charged micro- and nanochannels.." Anal Chem 74, no. 9, 2139-2150 - 2139-2150.

2000

  • Desai, T, A; Hansford, D, J; Ferrari, M, 2000, "Micromachined interfaces: new approaches in cell immunoisolation and biomolecular separation.." Biomolecular engineering 17, no. 1, 23-36 - 23-36.
  • T Desai, D Hansford, L Leoni, M Essenpreis, and M Ferrari, 2000, "Nanoporous anti-fouling silicon membranes for implantable biosensor applications." Biosensors and Bioelectronics 15, no. 9-10, 453-462 - 453-462.
  • Desai, T.A.; Hansford, D.J.; Ferrari, M., 2000, "Micromachined interfaces: new approaches in cell immunoisolation and biomolecular separation.." Biomol Eng 17, no. 1, 23-36 - 23-36.
  • Desai, T.A.; Hansford, D.J.; Leoni, L.; Essenpreis, M. et al., 2000, "Nanoporous anti-fouling silicon membranes for biosensor applications.." Biosens Bioelectron 15, no. 9-10, 453-462 - 453-462.

1999

  • P Belgrader, D Hansford, GTA Kovacs, K Venkateswaren, F Milanovich, S Nasarabadi, R Mariella, M Okuzumi, F Pourahmadi, and MA Northrup, 1999, "A minisonicator to rapidly disrupt bacterial spores." Analytical Chemistry 71, no. 19, 4232-4236 - 4232-4236.
  • Belgrader, P.; Hansford, D.; Kovacs, G.T.; Venkateswaran, K. et al., 1999, "A minisonicator to rapidly disrupt bacterial spores for DNA analysis.." Anal Chem 71, no. 19, 4232-4236 - 4232-4236.
  • Desai, T.A.; Hansford, D.J.; Kulinsky, L.; Nashat, A.H. et al., 1999, "Nanopore Technology for Biomedical Applications." Biomedical Microdevices 2, no. 1, 11-40 - 11-40.
  • Desai, T.A.; Hansford, D.; Ferrari, M., 1999, "Characterization of micromachined silicon membranes for immunoisolation and bioseparation applications." Journal of Membrane Science 159, no. 1-2, 221-231 - 221-231.

Presentations

  • "Cells on Gels: Biomimetic Micron-Scale Polyacrylamide Gel Substrates for Studies of GBM Cell Adhesion and Migration." 2017, Presented at Biomedical Engineering Society Meeting,
  • "Probing interclonal heterogeneities in patient-derived glioma stem cell populations via micro/nanoscale technologies." 2015, Presented at Biomedical Engineering Society Meeting,
  • "Probing the migratory behavior of patient-derived glioma stem cells on a micro-engineered platform - a single cell analysis." 2013, Presented at Biomedical Engineering Society Meeting,
  • "On-chip capture/sorting and characterization of cancerous cells." 2012, Presented at Biomedical Engineering Society Meeting,
  • "Micro/Nanoengineering Hormone-Expressing Islet-Like Tissue Subunits." 2011, Presented at Biomedical Engineering Society Meeting,
  • "Guided Tumor Cell Migration on Microscale Mimics of Contact Guidance Cues." 2011, Presented at Biomedical Engineering Society Meeting,
  • "Micropatterning Neuronal Networks on Nanofibers Platform." 2011, Presented at Biomedical Engineering Society Meeting,
  • "Adhesion and proliferation of mesenchymal stem cells on micropatterned thin films modified with nanohydroxyapatite particles." 2011, Presented at 3rd Joint Meeting of the European Calcified Tissue Society & the International Bone and Mineral Society,
  • "Microstructured coatings to study the behavior of osteoblast-like cells on hard materials." 2011, Presented at 3rd Joint Meeting of the European Calcified Tissue Society & the International Bone and Mineral Society,
  • "Guided Assembly of Insulin-Expressing Islet-Like Cell clusters on Polymeric Micro/Nanowells." 2010, Presented at Biomedical Engineering Society Meeting,
  • "Micropatterning and Printing of Functional Microscale Tissue Subunits on Nanofibrous Scaffolds." 2010, Presented at Biomedical Engineering Society Meeting,
  • "Evaluation of Electrospun Scaffolds for the Expansion of Precursors of Insulin-producing Cells." 2010, Presented at Biomedical Engineering Society Meeting,
  • "Validation and Characterization of an Acoustic Sensor Based on PVDF Micropillars and Patterned Electrodes." 2010, Presented at 3rd Annual Meeting of the ASME/AIAA Smart Materials, Adaptive Structures, and Intelligent Systems Conference,
  • "Polymer MEMS for Measuring Single Cell Forces." 2010, Presented at ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference,
  • "Zirconia Microtextured Surfaces Using Soft Lithography." 2010, Presented at 88th General Session and Exhibition of the International Association for Dental Research,
  • "Microstamped Silica Films on Curved Zirconia Surfaces." 2010, Presented at 88th General Session and Exhibition of the International Association for Dental Research,
  • "Anisotropic Microtextured Silica Thin Films on Zirconia." 2010, Presented at 88th General Session and Exhibition of the International Association for Dental Research,
  • "Portland Particulated Silica Coatings – Comparison between Two Coating Techniques." 2010, Presented at 88th General Session and Exhibition of the International Association for Dental Research,
  • "Micro-Structured Silica Coatings with HA Particles Using a PDMS Stamp." 2009, Presented at Materials Research Society Meeting,
  • "Combination of Micro- And Nanofabricated Structures for the Production of Biomimetic Tissue Engineering Scaffolds." 2009, Presented at Biomedical Engineering Society Meeting,
  • "Layer by Layer Microassembly of Multifunctional Bone Tissue Engineering Scaffolds." 2009, Presented at Biomedical Engineering Society Meeting,
  • "Polymer Microraceways for Characterization of Glioblastoma Cell Migratory Patterns." 2009, Presented at Biomedical Engineering Society Meeting,
  • "Controlled Pancreatic Cluster Formation on a Bed of Electrospun Fibers." 2009, Presented at Biomedical Engineering Society Meeting,
  • "Silica Coatings with Portland cement Particles for Dental Implant Surfaces Based on Sol-Gel Micromolding." 2009, Presented at Biomedical Engineering Society Meeting,
  • "Microfabricated SiO2 Thin Films on Structural Dental Ceramics." 2009, Presented at Bioceramics 22. International Symposium on Ceramics in Medicine,
  • "High throughput assembly of spatially controlled microscale tissue subunits." 2009, Presented at Society for Biomaterials Meeting,
  • "Bioactive Portland cement porous scaffolds." 2009, Presented at Society for Biomaterials Meeting,
  • "Design and microfabrication of a PVDF acoustic sensor." 2009, Presented at ASME Conference on Smart Materials, Automotive applications I,
  • "Acoustic sensor with PVDF micropillars and patterned electrodes." 2008, Presented at ASME Conference on Smart Materials, Adaptive Structures and Intelligent Systems,
  • "Polymer Micro-Nano Devices for Applications in Guided Cell Assembly." 2008, Presented at Biomedical Engineering Society Meeting,
  • "Spatially Controlled Aggregation of Pancreatic Cells in Microfabricated Wells on Polymer Membranes." 2008, Presented at Biomedical Engineering Society Meeting,
  • "Simultaneous Evaluation of Cell Proliferation and Gene Expression Via MTT-Coupled Real-Time RTPCR." 2008, Presented at Biomedical Engineering Society Meeting,
  • "Microwell Cell Traps for High Throughput Cell Isolation." 2008, Presented at . Biomedical Engineering Society Meeting,
  • "Microfabrication of Zeolite Membrane on Patterned Porous Alumina Support Using Soft Lithography." 2008, Presented at 12th International Meeting on Chemical Sensors,
  • "Evaluation of housekeeping gene stability during human bone marrow mesenchymal stem cells differentiation to the osteogenic lineage." 2008, Presented at 6th Annual Meeting of the International Society for Stem Cell Research,
  • "Biocompatibility, Bioactivity and Mechanical Properties of Portland cement and Portland cement-Metakaolin Blends for Bone Tissue Engineering Applications." 2008, Presented at Materials Research Society Meeting,
  • "Soft Lithographic Production of Electroactive Polyvinylidene Fluoride Microstructures for BioMEMS Technologies." 2008, Presented at BioMED 2008,
  • "Development of PDMS-reinforced Portland cement porous scaffolds for load-bearing bone tissue engineering applications." 2007, Presented at Second International Conference on Mechanics of Biomaterials and Tissues,
  • "Portland cement – Metakaolin blends as novel biomaterials for load bearing bone tissue engineering." 2007, Presented at Biomedical Engineering Society Meeting,
  • "Microfabricated Membranes for Isolation and Morphological Control of Cells." 2007, Presented at Biomedical Engineering Society Meeting,
  • "Fabrication of piezoelectric polyvinylidene fluoride (PVDF) microstructures by soft lithography for tissue engineering and cell biology applications." 2007, Presented at Materials Research Society Meeting,
  • "Fabrication of Biocompatible Portland cement Porous Scaffolds for Bone Tissue Engineering Applications." 2006, Presented at The 8th New Jersey Symposium on Biomaterials Science,
  • "Bioactive Coatings on Portland cement Substrates: Surface precipitation of Apatite-like Crystals." 2006, Presented at Materials Science & Technology 2006 Conference,
  • "Microfabrication of Degradable Polymer Tissue Engineering Scaffolds." 2006, Presented at Materials Science & Technology 2006 Conference,
  • "Biocompatibility improvement of Portland cement through the introduction of pozzolanic materials: Effects of Metakaolin on the cytotoxicity." 2005, Presented at . 2nd Colombian Congress of Bioengineering and Biomedical Engineering,
  • "Fabrication of Portland cement porous scaffolds: Potential applications as load bearing bone substitutes." 2005, Presented at 2nd Colombian Congress of Bioengineering and Biomedical Engineering,
  • "Bone Tissue Engineering applications of Portland cement Phase I: Biocompatibility studies – Effects of Calcium Hydroxide." 2005, Presented at Third International Materials Congress,
  • "Biocompatibility studies on Portland cement substrates: Potential Bone Tissue Engineering Applications." 2005, Presented at II Symposium about Biofactories, Biotechnology advances in Colombia,
  • "Microfabrication and in vitro evaluation of PLGA scaffolds." 2003, Presented at 1st Colombian Congress of Bioengineering and Biomedical Engineering,
  • "Identification of cardiac proteins in diabetic rats using proteomics." 2003, Presented at 1st Colombian Congress of Bioengineering and Biomedical Engineering,

Papers in Proceedings

2020

  • Hisey, C.L.; Mitxelena-Iribarren, O.; Martínez-Calderon, M.; Arana, S. et al. "Cancer cell trapping and migration in a microfluidic device for anti-migration drug screening." (1 2020).

2014

  • Gomez-Aranzadi, M.; Mujika, M.; Arana, S.; Hansford, D. "Microchannel Modification to Enhance the Sensitivity in Biosensors." (1 2014).

2009

  • Xu, J.; Dapino, M.J.; Perez, D.G.; Hansford, D. "Design and microfabrication of a pvdf acoustic sensor." (6 2009).
  • Pelaez-Vargas, A.; Ferrell, N.; Fernandes, M.H.; Hansford, D.J. et al. "Cellular alignment induction during early in vitro culture stages using micropatterned glass coatings produced by sol-gel process." (1 2009).

2008

  • Ferrell, N.; Schwan, S.; Spohn, U.; Heilmann, A. et al. "Measurement of forces generated by chemomechanical protein aggregates using polymer BioMEMS." (12 2008).
  • Apaydin, E.; Zhou, Y.; Hansford, D.; Koulouridis, S. et al. "Printing of patterned copper on pliable, microtextured PDMS/ceramic composites." (12 2008).
  • Gallego, D.; Ferrell, N.; Higuita, N.; Hansford, D.J. "Soft lithographic production of electroactive polyvinylidene fluoride microstructures for BioMEMS technologies." (12 2008).
  • Gallego, D.; Higuita, N.; Garcia, F.; Posada, O.M. et al. "Biocompatibility, bioactivity and mechanical properties of Portland cement and Portland cement-Metakaolin blends for bone tissue engineering applications." (12 2008).
  • Higuita, N.; Dai, Z.; Kaletunç, G.; Hansford, D.J. "Fabrication of pH-sensitive microparticles for drug delivery applications using soft lithography techniques." (12 2008).

2007

  • AJ Spiwak, S Warron, S Sullivan, C Sopkovich, DJ Hansford "Effect of pump operation on temperature change and weight change of a new tubing product for peristaltic pump operation." in Amer Soc Extracorp Tech. (4 2007).
  • I Tzanidis, CC Chen, D Hansford, and JL Volakis "Spiral antenna miniaturization using variable magnetic material loading." in URSI 2007. (7 2007).
  • DJ Hansford "Polymer-Ceramic Electro-Magnetic Composites for RF/Microwave Antennas and Circuits." in Composites at Lake Louise. (10 2007).
  • Hansford, D.J.; Sandhage, K.H. "Novel polymer-ceramic composites for conformable RF applications." (12 2007).
  • N Higuita, D Gallego, F Garcia, LE Lopez, C Sarassa, P Agudelo, AS Litsky, DJ Hansford "Development of polydimethylsiloxane-reinforced Portland cement porous scaffolds for load-bearing bone tissue engineering applications." in Int. Conf. Mech. of Biomaterials and Tissues. (12 2007).
  • Palacio, M.; Bhushan, B.; Ferrell, N.; Hansford, D. "Adhesion properties of polymer/silicon interfaces for biological micro-/nanoelectromechanical systems applications." (8 2007).
  • AJ Spiwak, C Sopkovich, T Preston, G Agarwal, DJ Hansford "A visualization of extracorporeal technology by atomic force microscopy to appreciate surface characteristics for blood and tissue interactions." in Amer Soc Extracorp Tech. (4 2007).

2006

  • D Gallego-Perez, N Ferrell, Y Sun, DJ Hansford "Microfabrication of degradable polymer tissue engineering scaffolds." in Symposium on Advanced Processing of Biomaterials. (10 2006).
  • SV Olesik, J Shearer, M Umaedi, N Ferrell, and DJ Hansford "Selective carbon microfabricated liquid chromatographic devices for separation of biomolecules." in HPLC Symposium 2006. (6 2006).
  • A Chakrapani, N Ferrell, DJ Hansford "Fabrication of Biodegradable Polymer Microdevices for Controlled Drug Delivery Systems." in Particles 2006: Medical/Biochemical Diagnostic, Pharmaceutical, and Drug Delivery Applications of Particle Technology. (5 2006).

2005

  • 1. D Gallego, LE Lopez, DJ Hansford, J Klemas "Bone Tissue Engineering applications of Portland Cement Phase I: Biocompatibility studies – Effects of Calcium Hydroxide." in Third International Materials Congress. (9 2005).
  • 1. D Gallego, N Higuita, F Garcia, DJ Hansford "Biocompatibility improvement of Portland Cement through the introduction of pozzolanic materials: Effects of metakaolin on the cytotoxicity." in Colombian Congress of Bioengineering and Biomedical Engineering, Bogotá, Colombia. (9 2005).
  • D Gallego, J Klemas, E Lopez, DJ Hansford "Biocompatibility studies on Portland Cement substrates: Potential Bone Tissue Engineering Applications." in II Symposium about Biofactories, Biotechnology advances in Colombia. (3 2005).
  • DJ Hansford "Polymer MEMS devices for homeland security sensing applications." in Working Together: R&D Partnerships in Homeland Security. (4 2005).
  • Tomasko, D.L.; Hansford, D.; Merrill, J.; Walters, W. "Panel - Nanotechnology curriculum and research opportunities in undergraduate engineering education." (12 2005).
  • He, H.; Guan, J.; Lee, L.J.; Hansford, D. "An oral delivery device based on self-folding hydrogels." (12 2005).
  • Grewell, D.; Ditmer, D.; Hansford, D.; Benatar, A. "Beam shaping with diffractive optics for laser micro-welding of plastics." (12 2005).
  • N Ferrell, J Woodard, and DJ Hansford "Polymer MEMS sensors for measuring single cell biomechanics." in Proc. 1st Internat'l Conf. Mech. of Biomat'ls & Tissues. (12 2005).
  • 1. D Gallego, N Higuita, F Garcia, DJ Hansford, E Lopez "Fabrication of Portland Cement porous scaffolds: Potential applications as load bearing bone substitutes." in Colombian Congress of Bioengineering and Biomedical Engineering,. (9 2005).
  • J Volakis, K Kurabayashi, and DJ Hansford "Miniature autonomous and wireless sensors based on nano-optofluidic microsystems for toxic gas detection." in Working Together: R&D Partnerships in Homeland Security (Dept. Homeland Sec. Sci. & Tech. Dir. (4 2005).

2004

  • N Ferrell, J Woodard, and DJ Hansford "Fabrication of a Polymer MEMS Sensor for Measuring Single Cell Biomechanics." in Proc IASTED Internat’l Conf Biomech. (8 2004).
  • N Ferrell, J Woodard, and DJ Hansford "Fabrication of Polymer MEMS for Biological Applications." in BioMEMS & Biomed Nanotech 2004 Conf. (8 2004).
  • Ferrell, N.; Woodard, J.; Hansford, D. "Design and fabrication of a polymer mems cell force sensor for measuring single cell biomechanics." (12 2004).

2003

  • DJ Hansford, D Gallego, D Patiño, D Calderón, N Ferrell, A Chakrapani "Microfabricación y evaluación in vitro de scaffolds en PLGA–ácido poli (DL-lactico-co-glicolico): Microfabrication and in vitro evaluation of PLGA scaffolds." in 1st Colombian Congress of Bioengineering and Biomedical Engineering. (10 2003).

1999

  • Desai, T.A.; Hansford, D.J.; Ferrari, M.; Rastellini, C. "Implantation of rat islet-filled micromachined biocapsules in mice." (12 1999).
  • Hansford, D.; Desai, T.; Ferrari, M. "Microfabricated membranes for immunoisolation." (12 1999).

1998

  • Desai, T.A.; Hansford, D.J.; Chu, W.H.; Huen, T. et al. "Investigating islet immunoisolation parameters using microfabricated membranes." in Symposium on Biomaterials Regulating Cell Function and Tissue Development at MRS Spring Meeting. (1 1998).
  • Hansford, D.; Desai, T.; Tu, J.; Ferrari, M. "Biocompatible silicon wafer bonding for biomedical microdevices." (12 1998).

1996

  • Ferrari, M.; Chu, W.; Desai, T.; Hansford, D. et al. "Silicon nanotechnology for biofiltration and immunoisolated cell xenografts." (1 1996).

1992

  • Chu, W.; Mehregany, M.; Hansford, D.; Pirouz, P. "Effect of thermal oxidation on residual stress distribution through the thickness of p+ silicon films." (12 1992).

Patents

  • Essenpreis,Matthias; Desai,Tejal,A; Ferrari,Mauro; Hansford,Derek,J. "Implantable Analyte Sensor." Patent number: 6405066
  • Guan,Jingjiao; Hansford,Derek,J; Lee,L,James. "Self-folding polymer microparticles." Patent number: 7364675
  • Hansford,Derek,J; Walczak,Robbie,J; Boiarski,Anthony,A; Albert Terrence Conlisk. "Nanopump devices and methods." Patent number: 7799197
  • "Electroosmotic devices for fluid handling."