Pilot grant advances engineering-medicine collaboration

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Biomedical Engineering and Neurosurgery Associate Professor Natalia Higuita-Castro and Nephrology Assistant Professor Nicholas Ferrell have earned a pilot grant from The Ohio State University Center for Medical and Engineering Innovation (CMEI) for their project titled "Targeted Cellular Delivery of Nanoengineered Extracellular Vesicles for Acute Kidney Injury."

The $35,000 pilot grants from CMEI support collaborations between Ohio State researchers who initiate promising ventures at the medicine-engineering interface, involving at least one faculty member from the College of Engineering and one faculty member from a health sciences college. The grant’s purpose is to accelerate interdisciplinary research projects.

Headshot of Natalia Higuita Castro, a woman of color

We appreciate the opportunity provided through this CMEI Pilot Grant to develop novel nanotechnology-enabled cell and gene therapies for Acute Kidney Injury. This is an excellent opportunity to propel new interdisciplinary research ideas with a strong emphasis on developing novel therapeutic.  -Natalia Higuita-Castro, PhD 

For their project, Natalia Higuita-Castro and Nicholas Ferrell will develop a cell-based gene delivery system for nanoengineered extracellular vesicles to target the kidney following acute injury. By preserving tissue function, this could reduce the high morbidity and mortality resulting from acute kidney injury and may become a platform for treatment of other renal disorders.


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